There are so many variables that without details , it all beleavers on one side or the other , then other sides = many sides .
Depending on the yr. of manufacture / or kits used when a part of a fuel system is rebuilt , the seals & gaskets vary a lot from multiple manufacturers - and they change there products over time .
Then you get into what each individual says is bio-diesel , this has even more variables - especially the closer to home made , even the commercial producers vary .
Leave the subject out of the filter waste vegi , heated oil types [ not that quality bio-diesel can not be made from used fryer oil { not enough volume for commercial manufactures } ] .
So then we step into real bio-diesel = transesterification process - basically removes the glyserin .
But there are multiple processes to do this , the most common uses methanol , another process [ much less common ] is the water process .
Then especially the home-brew and smaller producers , is how well the wash , water removal , filter , PH balance etc.
Then back to manufacturers , the engineering is moving away for any concept of any kind of bio [ except maybe to keep seals / gaskets from reacting to mandated small % of bio ] so to lockout bio & keep petro diesel .
So the only way to know for sure is to rebuild fuel system yourself and make your own [ then only you are responsible for the choices ] .
Bio-diesel can be totally non-problematic , but only within limits and you have to match you fuel system to the fuel .
Probably the single biggest issue is - lack of volume for general use , as compared to petro diesel [ not including political , and vested interests ] ,
There are some options to deal with the volume issue , but with all that is working against bio , the volume solution is economically un-viable -- that is producing vegi oil by algae method [ now who's semi desert area are we going to use to grow the volume ? ] .