I'm very happy with the mileage bump I just experienced on my last trip. One of my best, if not the best tank, I've gotten under these driving conditions.
There are definitely several new factors at play, not just the Kerma tune, but the tune is the main one. I recently put in a new MAF (mine was fine, but maybe not optimal). On the way up from sea level to ~8k and back down to Elk Grove Propel station (592 miles), I got 50.1 mpg (which is one of my best tanks ever) on B20. This was with AC on, big dog, wife, baby, luggage and altitude. I am very impressed.
In the second leg of the trip in Elk Grove, I was able to fuel up with Propel Fuels new renewable dieselHPR. So far, judging by what my fuel gauge is showing, this tank is on track to beat the last one by a decent margin (at least under the same highway driving conditions). More here:
http://forums.tdiclub.com/showpost.php?p=4772200&postcount=71