VWs hold up as well as any car with the same engine displacement on the autobahn.
In 2018 my wife and I were in Germany visiting our DIL's family. During our visit we drove the autobahn from Mannheim to Salzburg. I don't remember the exact route we took but we drove to Munich on day one, did some sight-seeing, then onto to Salzburg a few days later. I will give you my general observations of of what it's like for an American driving on the autobahn.
Compared to the US interstate highway system;
The autobahn is built for high speed. It's much smoother and much better maintained the the average US interstate. A newly paved section of US interstate is how an average section of the autobahn looks. Little by little the unrestricted sections of the autobahn are being restricted. Many sections of the autobahn have equivalent speed limits as the US interstate highways.
Off ramps are much shorter so you are on the brakes harder when exiting. On ramps have a merge lane to get up to speed with the slow traffic, equivalent to merging in the US. Exit signs are small and give you short notice, like 500m on average. Exits are rarely numbered so you have to know where you are going. We had a GPS in the car and we were using our phones with google maps a lot to double check things. We missed a few exits and turns but we always got back on track.
Rest stops exist, but not always with toilet facilities. WC for 'water closet' is what you are looking for when planning a stop. Fuel is available everywhere but it's pretty much just fuel. Huge US style truck-stops are rare. We saw one stop with a McD's, and it was very small by US truck-stop standards.
Now, for that high speed driving. When you get out of an urban area and the unlimited speed zone starts, you have to know and follow the protocols. All slower traffic keeps to the center lane, if there is one, or the right lane. I was in a C-class MB with a 2.2L gas turbo engine driving darn close to it's max of 135MPH in the left lane and before I could even merge right, I was getting passed on the right by impatient drivers going 160mph+. That was unnerving, having cars come up behind me so fast I couldn't react. High HP Porsche, BMW, and an Audi zipped around with the drivers flashing their lights and giving me the stink eye as they passed me. I was put in my place and stayed in the slower lanes. You don't hang out in the left lane with the big dogs with 250HP or less.
The left lane is speed unrestricted, BUT, it's also the passing lane for us slow-pokes. So initiating a lane change requires a lot more planning. The high end cars can be going 160+, maybe twice what you are. That means you look really hard at your mirrors to make sure that lane is clear before you pull out.
While driving in the slow lane around 80mph I saw a Ferrari go by me so fast it's tail lights looked like tracer bullets. I also saw a few Audi R8s, Porsches, BMWs, and a Mustang GT pushing 150MPH+. Must be fun? right? No. Even driving at 125MPH, what our car could easily handle, demanded way more concentration than what you think. You can't distract yourself with anything, of course no phone, no adjusting the HVAC, radio, and I rarely used the cruise control. Driving is much more dynamic than it is in the US.
Another thing that I found unnerving, late braking. While in the slow lane and watching the beautiful high end cars in the fast lane, I noticed how they come right up on someone and brake at the last second. Usually this was while someone was initiating a pass.
So how do VWs hold up on the autobahn? Very well because cars are better maintained in Europe. Owning a car is more expensive so people take better care of them. There is no driver's-ed in school. Everyone pays a private company to get a driver's license and it costs ~$1500 on average. High taxes on cars, parts, and fuel add up fast. I calculated fuel cost to the equivalent of ~$4.80/gallon. That will motivate one to slow down. No rusty beaters over there. I did see lots of nice older VWs in great shape.
The average German is a much better driver than a US driver. The cars are maintained better, and the roads are in much better condition. That's the Germans, watch your @ss around the Turks and Italians.